Dr. Morepen Itramore-100

Itraconazole is an azole antibiotic used to treat certain fungal infections that can appear anywhere on the body. When taken inside the body, the active ingredients inside Itraconazole will reach the affected area and gradually destroy the parasitic fungi that cause disease, thereby stopping the progression of the disease.

Itraconazole acts by inhibiting the fungal cytochrome P-450 dependent enzyme lanosterol 14-α-demethylase. When this enzyme is inhibited it blocks the conversion of lanosterol to ergosterol, which disrupts fungal cell membrane synthesis. Itraconazole exhibits fungistatic (slows the growth) activity against yeast-like fungi and fungicidal (kills the fungus) activity against Aspergillus spp.

Indications :-With its broad spectrum antifungal activity itraconazole is used to treat a variety of fungal infections including.

• Blastomycosis.
• Histoplasmosis.
• Aspergillosis.
• Sporotrichosis.
• Candidiasis.
• Onychomycosis.